A protein-protein docking benchmark.

Posted by Administrator on July 1, 2003 in Uncategorized

We have developed a nonredundant benchmark for testing protein-protein docking algorithms. Currently it contains 59 test cases: 22 enzyme-inhibitor complexes, 19 antibody-antigen complexes, 11 other complexes, and 7 difficult test cases. Thirty-one of the test cases, for which the unbound structures of both the receptor and ligand are available, are classified as follows: 16 enzyme-inhibitor, 5 antibody-antigen, 5 others, and 5 difficult. Such a centralized resource should benefit the docking community not only as a large curated test set but also as a common ground for comparing different algorithms. The benchmark is available at (http://zlab.bu.edu/~rong/dock/benchmark.shtml).

http://www.ncbi.nlm.nih.gov/pubmed/12784372

Chen R, Mintseris J, Janin J, Weng Z. A protein-protein docking benchmark. Proteins. 2003 Jul 1;52(1):88-91.